- Studied acting at Illinois State University.
- Has twice won Broadway's Tony Award as Best Actress (Featured Role - Play): in 1983 for "Steaming" and in 1985 for David Rabe's "Hurlyburly." She was also nominated as Best Actress (Play) in 1992 for "Park Your Car in Harvard Yard".
- She appeared in numerous TV commercials for products such as Greyhound buses, StaPuf fabric softener, Red Lobster restaurants and Gerber baby food.
- Discovered her love for drama when she acted in a high school production of "The Man Who Came to Dinner".
- Daughter, Margaret Elizabeth Braine (born 1989) and son, Thomas Carter Braine (born December 8, 1993) with her husband, Tim Braine.
- Will play "Sally Durant Plummer" in a limited-run revival of Stephen Sondheim's "Follies", to open on Broadway this spring. (January 2001)
- Listed as one of twelve "Promising New Actors of 1985" in John Willis' Screen World, Vol. 37.
- Worked at both Joseph Papp's Public Theater in New York and the Goodman Theater in Chicago after graduating from college.
- She was nominated for a 2008 Joseph Jefferson Award for Solo Performance for the play, "The Lady With All the Answers" at the Northlight Theatre in Chicago, Illinois.
- She was inducted into the Texas Film Hall of Fame in March 2004 in Austin, Texas.
- She was nominated for a 1978 Joseph Jefferson Award for Actress in a Principal Role in a Play for "The Goodbye People" at the Northlight Theatre in Chicago, Illinois.
- She has English, as well as some German, Scottish, and Welsh, ancestry.
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