- Is a breast cancer survivor. She was first diagnosed in October 2006.
- As of 2022 she only needs an Oscar to do the awards slam (referred to as an "EGOT"), which only 17 others have done.
- Was the only supporting character on Sex and the City (1998) to win an Emmy.
- Gave birth to her 2nd child at age 36, a son Charles Ezekiel Mozes on December 16, 2002. Child's father is her now ex-boyfriend, Danny Mozes.
- Grew up as the daughter of a single mother in a five-flight walk-up one-bedroom apartment in New York City, New York, USA.
- Gave birth to her 1st child at age 30, a son Samuel Joseph Mozes in November 1996. Child's father is her now ex-boyfriend, Danny Mozes.
- Was in a relationship with Danny Mozes from 1988 to 2003. They have 2 children together.
- Was up for the role of Dana Scully in The X Files (1993). The part was ultimately given to Gillian Anderson.
- (May 27, 2012) Married her girlfriend of 8 years Christine Marinoni following a 3-year-long engagement.
- Became a mother for the third time at age 44, when her son, Max Ellington Nixon-Marinoni was born February 7, 2011. Max was delivered by her fiancée (now wife), Christine Marinoni.
- Received her first Tony Award for "The Rabbit Hole" as "Best Leading Actress in a Play" on June 11, 2006.
- Won the 2017 Tony Award for "The Little Foxes" (Best Performance by a Featured Actress in a Play).
- In 2015, she made her debut as a stage director with the Broadway play "Rasheeda Speaking" starring Dianne Wiest and Tonya Pinkins.
- Has been an on and off Broadway actress since 1980.
- She and spouse, Christine Marinoni, the former New York director of the Alliance for Quality Education, continue to advocate together to increase financing for NYC's public schools.
- On March 19, 2018 she announced her run for the Democratic nomination for governor of New York, challenging incumbent Andrew Cuomo. She filed a petition with 65,000 signatures, more than four times the 15,000 required to force a primary election. Nixon ultimately lost the primary election to Cuomo 65%-34%.
- Guest star on the second episode of Law & Order (1990) and the second to last episode of Law & Order: Criminal Intent (2001).
- Cynthia attended Barnard College, the affiliated sister school of Columbia University, both primarily located in Manhattan, New York City, New York, USA. Barnard was founded in 1889 as a woman's college, in response to Columbia College's (some of the other colleges of Columbia University already admitted women by that time.) then refusal to admit women (Barnard is officially affiliated with, but legally and financially separate from Columbia), although the two schools feature shared classes, clubs, fraternities and sororities, sports teams, buildings, mostly overlapping and contiguous campuses, and more, plus Barnard students receive a diploma which is signed by the presidents of both Barnard and Columbia (and Barnard is named after Columbia's 10th president, Frederick Barnard). Although Columbia College and University became fully co-educational in 1983, Barnard continues as a women's only school to this day (as of 2020).
- In 1984-85, while still in her teens and still a high school student, Nixon appeared in two different Broadway plays simultaneously: Tom Stoppard's The Real Thing" and David Rabe's "Hurlyburly." This was possible because " "Hurlyburly" is a much longer play than "The Real Thing," and also because her character in "Hurlyburly," Donna, only appears in the very beginning and the very end of the play while her character in "The Real Thing," Debbie, is only in one scene during act 2. Both of these productions had the same director, Mike Nichols. In 2014, Nixon appeared in another Broadway production of "The Real Thing"--this time as Charlotte, Debbie's mother.
- Was nominated for Broadway's 1995 Tony Award as Best Actress (Featured Role - Play) for "Indiscretions."
- Appeared on the game show To Tell the Truth (1956) when she was nine years old; she was one of the impostors.
- Her father was from Texas and her mother was from Illinois. Her maternal grandfather was of German descent. Her other ancestry includes English, as well as some Scottish, Irish, and Welsh.
- A very liberal political activist, Nixon organized a May 2013 LGBT benefit for Bill deBlasio, a Democratic candidate running for mayor of New York City. She's also traveled around the U.S.campaigning to legalize gay marriage in several states, as well as speaking on behalf of Planned Parenthood in Washington, DC. In addition, she campaigned for President Obama's re-election in 2012 as well as for Minnesota Senator Al Franken.
- In the "Law & Order" (1990) episode "Subterranean Homeboy Blues" (1990), Nixon's future "Sex and the City" co-star Chris Noth reads Nixon's character her Miranda rights. "Miranda" is the name of Nixon's "Sex and the City" character.
- She studied drama at HB Studio in Greenwich Village in New York City.
- Daughter of Anne Nixon, a researcher for To Tell the Truth (1956) (Cynthia once appeared on the show as a mystery guest) and Walter Nixon.
- Two of her films held their world premiere at the Sundance Film Festival in 2015, James White (2015) and Stockholm, Pennsylvania (2015). The films premiered on the same day.
- Was number 88 on VH1's 100 Greatest Kid Stars (2005).
- Graduate of Hunter College High School in Manhattan, New York City, New York, USA.
- Nominated for the 2012 Tony Award for "Wit" (Best Performance by a Leading Actress in a Play).
- When she was a child actress, Nixon appeared in "Fifth of July," written by Lanford Wilson, on Broadway in New York City, New York, USA (and in a PBS broadcast of the stage play), and finally in the play-based TV movie of the same name (Fifth of July (1982)), which appeared on both Showtime and PBS (with the PBS version being self-censored for language and certain "adult themes," causing it to be approximately 14 minutes shorter than what was shown on Showtime. Only the PBS version is available on DVD).
- Was a guest at Sarah Jessica Parker's 40th birthday.
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