- In 2012, he was listed in The Hospital Club and Time Out's 100 influential people list, namely for his role as "Jim Moriarty" in the TV series, Sherlock (2010).
- From the Times of London newspaper of June, 2, 2019: He had come out to his loved ones years ago and was for a long time in a relationship with the writer Stephen Beresford, who in 2014 gave him one of his most "out" roles, in the rainbow-hued miners'-strike film Pride.
- According to his podcast interview on Elizabeth Day's How to Fail, Scott flunked out of Trinity College Dublin his first year for too many absences, but did not know it and showed up the first day of his second year only to be told to go home.
- He was awarded the 2010 Laurence Olivier Award for Outstanding Achievement in an Affiliate Theatre, along with fellow cast members Ben Whishaw, Katherine Parkinson and Paul Jesson, director James McDonald and playwright Mike Bartlett, for the Royal Court Theatre production of "Cock" by Mike Bartlett.
- In 2005, he won the Laurence Olivier Award for Outstanding Achievement or Performance in an affiliate Theatre for his performance in "A Girl in a Car With a Man".
- 2004: Named as one of European films' Shooting Stars by European Film Promotion.
- In 2007, he was nominated for a Drama League award for his Broadway performance, opposite Julianne Moore and Bill Nighy in "The Vertical Hour", by David Hare, directed by Sam Mendes.
- As of 2024, he has appeared in two films that were nominated for the Best Picture Oscar: Saving Private Ryan (1998) and 1917 (2019).
- Counts Irish actor Donal Donnelly as an early mentor and influence in his career, both having co-starred in Andrew's first feature film Korea (1995).
- His name is from the Greek name Andreas, which was derived from andreios "brave, manly, masculine", a derivative of ancient Greek "aner" (man).
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