28 wins & 32 nominations
- 1999 Winner American Comedy Award
- Funniest Female Performer in a TV Special (Leading or Supporting) Network, Cable or Syndication
Tied with Carol Burnett for _The Marriage Fool (1998)_. - 1998 Nominee American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1997 Winner American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1994 Nominee American Comedy Award
- Funniest Supporting Actress in a Motion Picture
- 1994 Nominee American Comedy Award
- Funniest Actress in a Motion Picture (Leading Role)
- 1995 Nominee CableACE
- Stand-Up Comedy Special or Series
Shared with: Louis J. Horvitz · Allan Baumrucker
- 2002 Winner Daytime Emmy
- Outstanding Talk Show
Shared with: Bernie Young · Laurie Rich · Janette Barber · Rob Dauber · Corin Nelson · Mimi Pizzi · John Redmann · Deirdre Arlt · Sharon Kelly · Liza Persky · Joy Trapani · Jeffry Culbreth · Deborah D'Amato · Christina Deyo · Shane Farley · Michelle Goin · Peter Killeen · Jennifer Lebeau · John McDaniel · Kim Miller · Terence Noonan · Maria Notaras · Lori E. Seid · Karen Yaeger - 2001 Winner Daytime Emmy
- Outstanding Talk Show
Shared with: Bernie Young · Laurie Rich · Corin Nelson · Rob Dauber · Deirdre Arlt · Mimi Pizzi · John Redmann · Joy Trapani · Janette Barber · Jeffry Culbreth · Deborah D'Amato · Christina Deyo · Sharon Kelly · Peter Killeen · John McDaniel · Kim Miller · Terence Noonan · Maria Notaras · Liza Persky · Heidi Safer · Karen Yaeger - 2001 Winner Daytime Emmy
- Outstanding Talk Show Host
Tied with Regis Philbin for Live with Kelly and Ryan (1988).
- 1999 Winner Primetime Emmy
- Outstanding Variety, Music or Comedy Special
Shared with: Walter C. Miller · Roy A. Somlyo - 1996 Nominee Primetime Emmy
- Outstanding Guest Actress in a Comedy Series
For episode "Eight". For playing herself. - 1995 Nominee Primetime Emmy
- Outstanding Individual Performance in a Variety or Music Program
- 1996 Nominee Golden Apple
- Female Star of the Year
- 2010 Nominee Image Award
- Outstanding Actress in a Television Movie, Mini-Series or Dramatic Special
- 2001 Winner TV Guide Award
- Talk-Variety Star of the Year
- 2023 Nominee Queerty
- Badass
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