- One of the few actors to have made guest appearances on all four of the Law & Order franchises.
- She was pre-med in college. She was studying to be a surgeon and participated in college plays. After 4 years of pre-med, she decided to become an actress.
- She was awarded the 1987 Joseph Jefferson Award for Actress in a Supporting Role in a Play for "The Normal Heart", at the Next Theatre Company in Chicago, Illinois.
- Has 3 children with her husband Lawrence Arancio: Liam, Emily and Trust Arancio.
- Daughter of John and Dolores (Clark) Dowd, and one of seven children. Her grandfather, James "Kip" Dowd, was a Major League baseball player for the Pittsburgh Pirates. The Dowd Agencies, an insurance company, was started by her great-grandfather.
- She was awarded the 1984 Joseph Jefferson Award Citation For Actress in a Principal Role in a Play for "Kennedy's Children", at the Pegasus Players in Chicago, Illinois.
- Nominated for the 2018 Emmy Award in the Supporting Actress in a Drama Series category for her role as Aunt Lydia in The Handmaid's Tale (2017), but lost to Thandiwe Newton from Westworld (2016).
- Won the 1993 Clarence Derwent award for "Candida", presented to outstanding newcomers to the New York theater scene.
- She was awarded the 1983 Joseph Jefferson Award Citation for Actress in a Principal Role in a Play for "A Different Moon", at the Next Theatre Company in Chicago, Illinois.
- Attended Goodman School of Drama (now The Theatre School at DePaul University) in Chicago.
- Has 4 sisters and 2 brothers: Kathleen, Elizabeth, Clare, Deborah, John and Gregory Dowd.
- She spent $13,000 of her own money to print and send DVDs of Compliance (2012) to Academy members in hopes of landing an Oscar nomination, but was not nominated.
- Bronx, New York (February 2009)
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