- He is the older brother of Paul Giamatti.
- He is the son of Toni Marilyn (Smith), an actress, and Bart Giamatti, late president of Yale University and the major league baseball commissioner who banished Pete Rose from baseball.
- Marcus' great grandfather, Commodore Alfred Brown, was the first and only man to swim the Panama Canal. This was accomplished in 1913, before the canal was opened to commercial traffic.
- Commodore Brown also assisted Houdini, placing chains and locks on his trunk, and then helping to lower him into one of Manhattan's rivers. He was there as well to rescue Houdini, if he needed it.
- Marcus majored in African Ethnomusicology at Bowdoin College, writing his thesis on Ashanti Tribal Funeral Music.
- Marcus also writes feature essays on baseball for MLB Insider's Club Magazine.
- A long time student of the Japanese martial art Ninpo (Ninjutsu).
- His grandmother, Kathryn E. Brown Smith, won the silver medal at the Nationals, in 1927 and 1929, in the 10 meter platform high dive event.
- Marcus and his wife Bree have 3 daughters, Ophelia Rosalee, Floralina Delilah and Magnolia Pearl..
- Is a graduate of the Yale School of Drama.
- A huge Boston Red Sox fan, and Major League Baseball fan.
- Threw out the ceremonial first pitch, before the start of Game 1 of the 1989 World Series, in Oakland, CA.
- He has played in The Legends and Celebrity Softball Game as part of The Major League All Star Game, 3 times in Pittsburgh (2006), San Francisco (2007) and Anaheim (2010).
- The original bass player for the Southern California jam band the Rebel Soul Band.
- Marcus was a bass student of Jim Stinnett, and The Stinnett School Of Music, an affiliate of The Berklee College of Music, in Boston.
- Has performed many of Shakespeare's greatest roles from Henry in "Henry V", to the tittle role in "Macbeth", to Bottom in a Midsummer Night's Dream, and Silvius in "As You Like It'".
- Marcus wrote the Afterword for the 2011 reissue of A. Bartlett Giamatti's book Take Time For Paradise, from Bloomsbury Press.
- Plays the electric bass guitar professionally.
- His bass recording work includes sessions with such distinguished musicians as Doug Pettibone, Don Heffington, Skip Edwards, Otis Hayes.
- Marcus has 3 daughters: Ophelia Rosalee, Floralina Delilah and Magnolia Pearl.
- Marcus received his Actor's Equity card at The Williamstown Theater Festival in 1987.
- Received the Carol Dye Award for Excellence in Acting upon his graduation from The Yale School Of Drama.
- His grandfather, Abram E. Smith, was the head football coach at Plainfield High School, in New Jersey, from 1943 to 1968. One of his players was Olympic Decathalon Champion Milton Campbell.
- Marcus originated the role of Tom Jackson, in the debut Broadway production of Horton Foote's Pulitzer Prize winning and Tony nominated play, The Young Man From Atlanta.
- He was the Captain of his high school varsity swimming team, as a senior, at Hopkins, in New Haven, Connecticut.
- Marcus was a member of the Bowdoin College Varsity Swimming Team. He specialized in the 50 and 100 yard Freestyle.
- Played the role of Marlowe, in Goldsmith's "She Stoops To Conquer" at The Seattle Rep, The Guthrie and Long Wharf.
- At Bowdoin College Marcus received The Alice Merrill Mitchell Award for Acting, as a graduating senior.
- Brother-in-law of Elizabeth Giamatti.
- His paternal grandfather, Valentine John Giamatti, was born in New Haven, New Haven Co., Connecticut, to Italian parents, from Campania. His paternal grandmother, Mary Claybaugh (Walton), was born in Wakefield, Middlesex, Massachusetts, and was of largely English descent, with deep Colonial American roots in Massachusetts and Maine. Marcus' mother's ancestry included German, English, Dutch, Irish, and distant Scottish and French.
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