The drawings of characters during the end credit roll were all done by the children of the animators. The same is true of the picture that Sid draws of himself on a cave wall. Sid's drawing was done by 3 year old Will Shefelman, son of a story artist Dan Shefelman. The story artist working on the scene was having difficulty drawing like a 3 year old so he consulted an expert.
John Leguizamo tried 30 different voices for Sid. After viewing a documentary about sloths, he learned that they store food in their mouths; this led to him wondering what he would sound like with food in his mouth. After attempting to speak as if he had food in his mouth, he decided that it was the perfect voice for Sid.
Despite the Dodo's less than brilliant survival instincts, they outlived all of the major character's species. Dodos were wiped out around the mid to late 17th century, whilst woolly mammoths (Manny) died out 10,000 years ago (a dwarf race existed until 1700 BC), ground sloths (Sid) are widely accepted to have become extinct some 2500 BC (although it has been proposed a small group survived till 1550 AD), and saber tooth tigers (Diego) were wiped out around 10,000 BC. Not even Neanderthals like Roshan and his father survived the Dodo.
All the actors were encouraged to improvise as much as possible to help keep the animation spontaneous.
The humans are not Homo-Sapiens, but Neanderthals. They never speak in the film.