Unlike previous shows, such as Mater's Tall Tales (2008) and Tales from Radiator Springs (2013) (excluding Bugged (2013) and The Radiator Springs 500½ (2014)), this series marks the first time Owen Wilson voiced Lightning McQueen outside of the movies since basically the theme park Lightning McQueen's Racing Academy (2019).
The second Disney Plus original series based off a Pixar film, after Monsters at Work (2021).
The Pizza Planet truck Todd makes multiple appearences in the series.
Characters from the Planes spin-off series were reportedly going to appear in the show but didn't for unknown reasons.