Mae Whitman and Miles Heizer are real life roommates.
Maura Tierney was originally cast as Sarah. NBC moved the show's originally slated fall release to mid-season, when Tierney was diagnosed with breast cancer. Due to her cancer treatment, she eventually had to leave the show and Lauren Graham replaced her.
Darin Heames played Seth Holt in the pilot but was replaced by John Corbett when the character next appeared in season 2.
In almost every episode, someone makes pancakes or waffles.
Showrunner Jason Katims, who previously ran the show "Friday Night Lights", cast many "FNL" actors on "Parenthood" in recurring or guest roles, including Michael B. Jordan, Minka Kelly, Matt Lauria, Jurnee Smollett-Bell, Jeff Rosick, Angela Rawna, Derek Phillips and Scott Porter.
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