Trivia

The series was created by Camilo Cano and Juana Uribe who are both closely tied with Pablo Escobar. Camilo Cano is the son of Guillermo Cano who was the publisher of newspaper El Espectador and who was murdered by Escobar in December 1986. Juana Uribe is the vice president of Caracol TV and also the series' producer. She is the daughter to Maruja Pachón who was kidnapped by Pablo Escobar on 7 November 1990 and later released. Juana is also the niece to presidential candidate Luis Carlos Galán who was killed by Escobar in August 1989.

Andrés Parra's portrayal of Pablo Escobar was so good that he was asked to reprise this role on other series or soap operas related to drug dealers. Although he was well paid for those roles, he felt that he was starting to be heavily pigeonholed in that character.

Real footage from newsreels and other media were used on several sections of the series in order to recreate better the situations that Colombia lived from the 1970s until the late 1990s.

It took almost a year (10 months) to film the whole series.

It's been implied that most of the cast was given a lot of video tapes, not only from Pablo Escobar, but all his family and some other interviews or speeches he gave. This would serve for the actors to completely adapt the mannerisms and sayings of each character and make it more realistic.