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MEIS1

Protein-coding gene in humans From Wikipedia, the free encyclopedia

MEIS1

Homeobox protein Meis1 is a protein that in humans is encoded by the MEIS1 gene.[5][6]

Quick Facts Available structures, PDB ...
MEIS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMEIS1, Meis homeobox 1
External IDsOMIM: 601739; MGI: 104717; HomoloGene: 135741; GeneCards: MEIS1; OMA:MEIS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002398

NM_001193271
NM_010789

RefSeq (protein)

NP_002389

NP_001180200
NP_034919

Location (UCSC)Chr 2: 66.43 – 66.57 MbChr 11: 18.83 – 18.97 Mb
PubMed search[3][4]
Wikidata
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Function

Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.[6]

Interactions

MEIS1 has been shown to interact with PBX1[7][8][9] and HOXA9.[7][10]

References

Further reading

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