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GABBR2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

GABBR2

Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.[5]

Quick Facts Available structures, PDB ...
GABBR2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGABBR2, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, gamma-aminobutyric acid type B receptor subunit 2, EIEE59, NDPLHS, DEE59
External IDsOMIM: 607340; MGI: 2386030; HomoloGene: 55902; GeneCards: GABBR2; OMA:GABBR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005458

NM_001081141

RefSeq (protein)

NP_005449

NP_001074610

Location (UCSC)Chr 9: 98.29 – 98.71 MbChr 4: 46.66 – 46.99 Mb
PubMed search[3][4]
Wikidata
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Function

B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM][5]

Interactions

GABBR2 has been shown to interact with GABBR1.[6]

See also

References

Further reading

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