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HLA-B35

Human leukocyte antigen serotype From Wikipedia, the free encyclopedia

HLA-B35

HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products.[1] B35 is one of the largest B serotype groups, it currently has 97 known nucleotide variants and 86 polypeptide isoforms. (For terminology help see: HLA-serotype tutorial). This variant is particularly susceptible to HIV infection.

Computer illustration of HLA-B*3508 with EBV (EPLPQGQLTAY) in the binding pocket.
B*3508-β2MG with bound peptide
2h6p
major histocompatibility complex (human), class I, B35
Alleles B*3501, 3502, 3503, . . .
Structure (See HLA-B)
Symbol(s) HLA-B2fyy, 2fz3
EBI-HLA B*35012h6p, 2cik,
1a1n
EBI-HLA B*3502
EBI-HLA B*3503
EBI-HLA B*3504
EBI-HLA B*3505
EBI-HLA B*3506
EBI-HLA B*3507
EBI-HLA B*35082nw3, 2nx5
EBI-HLA B*3509
EBI-HLA B*3510
EBI-HLA B*3511
EBI-HLA B*3512
Locus chr.6 6p21.31

Serotype

B35 serotype recognition of Some HLA B*35 allele-group gene products[2]
B*35B35 Sample
allele % %size (N)
3501982023
3502721013
3503941226
350410026
350594231
35067910
350891349
3509683
35107512
35116717
351278422
35147929
35204223

References

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