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HOXD9

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

HOXD9

Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene.[5][6][7]

Quick Facts Identifiers, Aliases ...
HOXD9
Identifiers
AliasesHOXD9, HOX4, HOX4C, Hox-4.3, Hox-5.2, homeobox D9
External IDsOMIM: 142982; MGI: 96210; HomoloGene: 8409; GeneCards: HOXD9; OMA:HOXD9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014213

NM_013555

RefSeq (protein)

NP_055028

NP_038583

Location (UCSC)Chr 2: 176.12 – 176.12 MbChr 2: 74.53 – 74.53 Mb
PubMed search[3][4]
Wikidata
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Function

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.[7]

See also

References

Further reading

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