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SDCCAG8

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

SDCCAG8

Serologically defined colon cancer antigen 8 is a protein that in humans is encoded by the SDCCAG8 gene.[5][6] This protein localizes to the centrioles.[7]

Quick Facts Identifiers, Aliases ...
SDCCAG8
Identifiers
AliasesSDCCAG8, BBS16, CCCAP, CCCAP SLSN7, NPHP10, NY-CO-8, SLSN7, hCCCAP, HSPC085, serologically defined colon cancer antigen 8, SHH signaling and ciliogenesis regulator SDCCAG8
External IDsOMIM: 613524; MGI: 1924066; HomoloGene: 4839; GeneCards: SDCCAG8; OMA:SDCCAG8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_029756
NM_001357390

RefSeq (protein)

NP_084032
NP_001344319

Location (UCSC)Chr 1: 243.26 – 243.5 MbChr 1: 176.81 – 177.02 Mb
PubMed search[3][4]
Wikidata
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Clinical significance

Mutations in SDCCAG8 have been found to cause nephronophthisis-related ciliopathies.[7]

Interactions

SDCCAG8 has been shown to interact directly with OFD1, a protein that is also associated with nephronophthisis-related ciliopathies.[7]

References

Further reading

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