The Flintstone Comedy Show

The series also featured new characters (the Frankenstones, the Cavemouse) as well as older characters (Penny, Wiggy, Moonrock and Schleprock of 1971's The Pebbles and Bamm-Bamm Show and 1972's The Flintstone Comedy Hour on CBS, Al Capp's the Shmoo from his show The New Shmoo which aired on NBC in 1979, and Captain Caveman from his own series on ABC in 1977 which lasted three seasons).

A series of gags, educational spots, games, how-to-draw and a dance-of-the-week were featured in-between the six segments every week. In 1982, reruns of the show were repackaged for two seasons under the title The Flintstone Funnies.

• Gay Autterson as Betty Rubble, Wiggy Rockstone
• Mel Blanc as Barney Rubble, Captain Caveman/Chester, Dino, Pterodactyl (in "R.V. Fever", "Clownfoot", "Sands of the Saharastone"), Turtle (in "Sands of the Saharastone"), Lizardsaurus #1 (in "Off the Beaten Track"), Lizardsaurus #2 (in "Off the Beaten Track"), Turtlesaurus (in "Gold Fever"), Igorstone (in "Monster Madness"), Joe (in "Bedlam on the Bedrock Express"), Herman (in "Vuclan"), Dragonasaurus (in "The Incredible Hunk", "Futuro"), Mr. Clods (in "Country Clubbed"), Doorman (in "Country Clubbed")
• Henry Corden as Fred Flintstone, Police Officer (in "Fred Goes Ape"), Stegosaurus (in "The Animal Master"), Max (in "Follow That Dogosaurus")
• Ruta Lee as Hidea Frankenstone
• Kenneth Mars as Lou Granite ("Captain Caveman" segment), Narrator ("Captain Caveman" segment), Mummy (in "The Mummy's Worse")
• Mitzi McCall as Penny Pillar
• Don Messick as Bad-Luck Schleprock
• Charles Nelson Reilly as Frank Frankenstone
• Paul Reubens as Freaky Frankenstone, Beaversaurus (in "Clone for a Day")
• Zelda Rubinstein as Atrocia Frankenstone
• Michael Sheehan as Bamm-Bamm Rubble, Punk Rock (in "Punk Rock")
• John Stephenson as Mr. Slate, Big Bronto Billy (in "The Ghost Sitters"), Sheik (in "Sands of the Saharastone"), Mr. Hardrock (in "Country Club Clods"), Robert (in "The Gourmet Dinner"), Sandy Granitebelt (in "The Great Bedrock Air Race"), Health Inspector (in "Getting the Business"), The Great Flintstoni (in "Fred's Big Top Flop"), The Grand Woolly Mammoth (in "Three Days of the Mastodon"), Brother Quartz (in "Three Days of the Mastodon")
• Russi Taylor as Pebbles Flintstone, Cavemouse ("Dino and Cavemouse" segments"), Cavemouse's Girlfriend (in "Dinner for Two"), Batmouse (in "Bat's All")
• Jean Vander Pyl as Wilma Flintstone, Mrs. Goldnugget (in "The Ghost Sitters"), Mrs. Boulder (in "Follow That Dogosaurus"), Mrs. Slate (in "The Gourmet Dinner"), Sinistra (in "A Night of Fright")
• Lennie Weinrib as Moonrock Crater, Sgt. Boulder, Big Louie (in "Off the Beaten Track"), Mr. Sandblaster (in "The Witch of the Wardrobe"), Boss (in "Follow That Dogosaurus"), Harry (in "Bedlam on the Bedrock Express"), Mr. Redbluff (in "Rockjaw Rides Again"), Hotwire Harry (in "Hot Air to Spare"), Robert Redrock (in "The Stand-In"), Mayor of Bedrock (in "Shore Thing")
• Frank Welker as Shmoo, Rockjaw, George the Gorillasaurus (in "Fred Goes Ape"), Clownfoot (in "Clownfoot"), Babyface (in "Off the Beaten Track"), Bearasaurus (in "Gold Fever"), Cousin Gruesome (in "A Night on the Town"), Usher (in "A Night on the Town"), Mammoth (in "Bogged Down"), Wolfasaurus (in "Monster Madness"), Rocky James (in "Bedlam on the Rocky Express"), T.V. Screenstone (in "A Stone is Born"), Duckasaurus (in "Pretty Kitty"), Lloyd the Sabretooth Tiger (in "Pretty Kitty"), Rocco DeRocco (in "The Stand-In"), Gopher (in "The Stand-In"), Roller Robber (in "The Roller Robber"), Sparky Granite (in "Put Up Your Duke"), Announcer (in "Sand Doom"), Winnie the Wondersaurus (in "Pet Peeves"), Winnie the Wondersaurus' Mom (in "Pet Peeves"), Mr. Rockley (in "Fred's Big Top Flop"), Charlie (in "Barney and the Bandit")

After ending its original time slot, The Flintstone Comedy Show was later repackaged as The Flintstone Funnies from September 18, 1982 to September 8, 1984,^[3] which consisted of reruns of the six segments (two and/or three segments aired per half-hour episode).^[6] The Flintstone Funnies is the final incarnation of The Flintstones that premiered on NBC.^[1]

Reruns of "Dino and the Cavemouse" aired on the Disney Channel adaption of Wake, Rattle, and Roll. Several of the Captain Caveman segments were featured on the Chip and Pepper's Cartoon Madness, which was only seen during the Fall 1991 season on NBC (couple of the segments showed the bulldog caricatures of the identical twin hosts briefly during the narrations).