8000 For identifiable analysis, provide information on transforming confidence intervalls · Issue #242 · sebapersson/PEtab.jl · GitHub
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For identifiable analysis, provide information on transforming confidence intervalls #242
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@sebapersson

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@sebapersson

If a confidence interval is computed using FIM (or ideally profile-likelihood), for a parameter on log10 or log scale, it can be relevant for users to get the interval on linear scale. This is not a trivial computation, as in a sense we are making a change of distribution, for example for log10 we have for the mean μ and sd σ:

function convert_log10_to_linear(μ_log, σ_log)
    μ_log = log(10) * μ_log
    σ_log = log(10) * σ_log
    μ_lin = exp(μ_log + 0.5 * σ_log^2)
    σ_lin = sqrt(exp(2 * μ_log + σ_log^2) * (exp(σ_log^2) - 1))
    return μ_lin, σ_lin
end

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