8000 CreativeLuchi (BOLANLE OLUCHI) Β· GitHub
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CreativeLuchi/README.md

Hi there, I'm BolanleπŸ‘©πŸ½β€πŸ”¬πŸ‘©β€πŸ’»πŸ‘‹

β˜„οΈ I am a science researcher specializing in Protein Chemistry, Bioinformatics and Computational Biology with a focus on molecular biology, biotechnology, drug discovery, and genomics. My expertise includes sequence analysis, structural biology, molecular docking, and pharmacokinetic prediction, supported by strong skills in data processing, assembly, and downstream functional analysis.

Screenshot 2025-06-12 at 22 52 11

🎯 Areas of Expertise Sequence Analysis: Proficient in nucleotide and protein sequence alignment, conserved region identification, and variant analysis using tools such as BLAST, Clustal Omega, and Jalview. Structural Biology: Experienced in analyzing protein structures, identifying active sites, and interpreting ligand-protein interactions using PDB data. Molecular Docking: Skilled in docking simulations with SwissDock and visualization of docking results using PyMOL and ChimeraX to elucidate drug binding mechanisms. Pharmacokinetics and Toxicity Prediction: Knowledgeable in ADMET profiling to assess drug-likeness, metabolism, and safety parameters. Next-Generation Sequencing (NGS) and Nanopore Data Analysis: Processing raw sequencing data (FASTQ, FAST5), quality control, alignment, assembly, and gene expression quantification. PCR and RT-PCR Data Analysis: Experienced in handling raw PCR data formats, normalization, and quantitative gene expression analysis.

🎯 Tools and Software Molecular visualization: ChimeraX, PyMOL, SwissDock Sequence and alignment: BLAST, Clustal Omega, Jalview Data processing and analysis: FastQC, Trimmomatic, BWA, Minimap2, featureCounts, DESeq2 Programming and scripting: R, Python (for statistical and bioinformatics analyses)

🎯 Research Interests Viral protease structure-function relationships and inhibitor design, Computational drug discovery and repurposing, Functional genomics and transcriptomics, Integration of multi-omics data for disease understanding

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  1. Mpro-Nirmatrelvir-Drug-Inhibition Mpro-Nirmatrelvir-Drug-Inhibition Public

    Comprehensive Structural and Functional Insights into SARS-CoV-2 Main Protease (Mpro) and its Inhibition by Nirmatrelvir: Sequence Conservation, Binding Mechanism, and Drug Efficacy Assessment.

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  2. HackBio_Coding_Internship-1.0 HackBio_Coding_Internship-1.0 Public

    Forked from aloyetunde/HackBio_Coding_Internship

    Python

0