TOMAS is a Python package for TOtal-MRNA-Aware Single-cell RNA-seq data analysis. TOMAS provides a computational control of total mRNA contents in droplet-based single cell RNA-seq data. It empowers accurate scRNA-seq analysis for datasets with large total mRNA content differences between cell types. TOMAS paves the way for future large-scale, low per-cell cost, doublet-rich droplet-based scRNA-seq experiments, which improves the sensitivity and the statistical power in detecing and studying rare cell types.
- Read the documentation.
- Install via
pip install tomas.