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A scientific reasoning model, dataset, and reward functions for chemis 8000 try.

Python 10 2 Updated Jun 5, 2025

MESS: Modern Electronic Structure Simulations

Python 30 2 Updated Mar 31, 2025
Python 64 6 Updated May 29, 2025

Implicit Solvent Approach Based on Generalised Born and Transferable Graph Neural Networks for Molecular Dynamics Simulations

Jupyter Notebook 41 1 Updated Apr 30, 2025

PLACER is graph neural network for local prediction of protein-ligand conformational ensembles.

Python 130 20 Updated Mar 7, 2025

cuEquivariance is a math library that is a collective of low-level primitives and tensor ops to accelerate widely-used models, like DiffDock, MACE, Allegro and NEQUIP, based on equivariant neural n…

Python 217 12 Updated May 27, 2025

AI-augmented R-group exploration in medicinal chemistry

Python 17 2 Updated Sep 25, 2024

Discriminator for Model Docking

Python 10 1 Updated Dec 20, 2024

ML models for pKa predictions

Python 2 Updated Apr 1, 2025

The official sources for the RDKit library

HTML 2,938 924 Updated Jun 5, 2025

Some useful RDKit functions

Jupyter Notebook 183 32 Updated May 12, 2025

bioinformatics tools running on modal

Python 90 12 Updated Jun 4, 2025

Experimental and calculated small molecule hydration free energies

Python 116 54 Updated Oct 14, 2022

AI-powered ab initio biomolecular dynamics simulation

Python 508 66 Updated Feb 18, 2025

A deep learning framework for molecular docking

C++ 8000 724 158 Updated May 23, 2025

The official repository of Uni-pKa

Python 60 13 Updated Apr 1, 2025
Python 34 7 Updated Oct 8, 2024

ai_in_chemistry_workshop

Jupyter Notebook 77 16 Updated Sep 16, 2024

SE(3) Equivariant Augmented Coupling Flows. NeurIPS 2023.

Python 24 5 Updated Mar 22, 2024

The official implementation of LinkerNet: Fragment Poses and Linker Co-Design with 3D Equivariant Diffusion (NeurIPS 2023 Spotlight)

Python 12 3 Updated Feb 23, 2024
Python 2 Updated Dec 10, 2024

basis

Python 1 Updated Jan 8, 2025

Implementation of Alphafold 3 from Google Deepmind in Pytorch

Python 1,446 188 Updated Jan 22, 2025

Mindless molecule generator in a Python package.

Python 24 4 Updated Apr 10, 2025

Chai-1, SOTA model for biomolecular structure prediction

Python 1,654 219 Updated Jun 3, 2025

Lo-Hi Splitter for Modern Splits of Molecular Datasets

Jupyter Notebook 52 2 Updated Oct 16, 2024

High level API for using machine learning models in OpenMM simulations

Python 5 1 Updated Oct 29, 2024
Jupyter Notebook 58 1 Updated May 17, 2025

tmQM dataset files

q 53 7 Updated Mar 17, 2025
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