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Inference code for scalable emulation of protein equilibrium ensembles with generative deep learning

Python 386 65 Updated Jun 11, 2025

[ICML 2025] 🧬 ReQFlow: Rectified Quaternion Flow for Efficient and High-Quality Protein Backbone Generation

Python 79 5 Updated May 15, 2025

FoldFlow: SE(3)-Stochastic Flow Matching for Protein Backbone Generation

Jupyter Notebook 232 19 Updated Dec 10, 2024

fpocket is a very fast open source protein pocket detection algorithm based on Voronoi tessellation. The platform is suited for the scientific community willing to develop new scoring functions and…

C 354 67 Updated Sep 9, 2024

The Biochemical Library (BCL) integrates traditional small molecule cheminformatics tools with machine learning-based quantitative structure-activity/property relationship (QSAR/QSPR) modeling. The…

C++ 28 19 Updated Feb 14, 2024

Evolutionary Scale Modeling (esm): Pretrained language models for proteins

Python 3,648 701 Updated Feb 7, 2024
Python 35 5 Updated May 24, 2025

Implementation of DiffDock: Diffusion Steps, Twists, and Turns for Molecular Docking

Python 1,261 301 Updated May 2, 2025

Public RFDiffusionAA repo

Python 397 76 Updated Jul 9, 2024

Fast, accurate antibody structure prediction from deep learning on massive set of natural antibodies

Python 362 67 Updated Sep 3, 2023

Deep learning framework for protein sequence design from a backbone scaffold that can leverage the molecular context including non-protein entities.

Jupyter Notebook 44 9 Updated Nov 24, 2024

Official repository for the Boltz biomolecular interaction models

Python 2,765 409 Updated Jun 12, 2025

In Silico Optimization of Protein Interaction Energies

R 1 Updated Oct 3, 2024

MaSIF-neosurf: surface-based protein design for ternary complexes.

Python 126 17 Updated Jun 5, 2025

HyperMPNN ‒ A general strategy to design thermostable proteins learned from hyperthermophiles

Jupyter Notebook 56 10 Updated May 20, 2025

Code for the ProteinMPNN paper

Jupyter Notebook 1,303 361 Updated Aug 14, 2024

Python package and command line tool for epitope prediction

Jupyter Notebook 51 22 Updated Aug 2, 2024

The Rosetta Bio-macromolecule modeling package.

C++ 274 91 Updated Jun 10, 2025

A tutorial for 3D computer graphics for bio-molecules and organic molecules

28 2 Updated Jan 26, 2025

Fast and dirty GPT injection into PyMOL

Python 6 Updated Apr 26, 2023

Protein-Ligand Binding Affinity Prediction with GNN and Transfer Learning From Protein Language Models

Python 27 8 Updated Jun 3, 2025

Chai-1, SOTA model for biomolecular structure prediction

Python 1,664 220 Updated Jun 3, 2025

Making Protein Design accessible to all via Google Colab!

Python 740 176 Updated Jun 9, 2025

User friendly and accurate binder design pipeline

Python 559 121 Updated Jun 11, 2025

AlphaFold 3 inference pipeline.

Python 6,600 837 Updated Jun 12, 2025

DiffLinker: Equivariant 3D-Conditional Diffusion Model for Molecular Linker Design

Python 334 47 Updated Apr 17, 2024

ColabFold on your local PC

Python 709 161 Updated Apr 22, 2025

Pymol ScrIpt COllection (PSICO)

Python 2 2 Updated Oct 20, 2023
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