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Readings for "A Unified View of Relational Deep Learning for Drug Pair Scoring." (IJCAI 2022)

95 14 Updated Aug 7, 2022

LD Score Regression in R

R 45 4 Updated Sep 10, 2023

An analytical approach for GWAS-by-Subtraction

R 12 1 Updated May 27, 2025

A tool to build a website to browse hundreds or thousands of GWAS.

Python 176 74 Updated Jul 31, 2024

Code supporting analyses in paper on fine-mapping AD loci

R 15 13 Updated Jun 28, 2021

High-Dimensional Gene Expression and Morphology Profiles of Cells across 28,000 Genetic and Chemical Perturbations

Jupyter Notebook 48 9 Updated Jan 26, 2025

Improving pathogenicity prediction of missense variants by using AlphaFold-derived features

R 8 4 Updated Aug 25, 2023

The fastai book, published as Jupyter Notebooks

Jupyter Notebook 23,172 8,924 Updated Aug 16, 2024

R package for the format conversion from bgen to gds

C++ 3 1 Updated Mar 3, 2025

Watershed implementation for African American samples from GTEx

R 2 Updated Feb 22, 2022

Drug gene set analysis (DRUGSETS) is a command line interface (CLI) tool implemented in python to perform genetically informed drug repositioning using drug gene set analysis in MAGMA.

Python 5 4 Updated Aug 17, 2022

a place for topmed workflows

WDL 12 23 Updated Feb 3, 2022

PolyFun (POLYgenic FUNctionally-informed fine-mapping)

Python 116 23 Updated Dec 9, 2024

identifying disease critical cell types and programs from single cell RNAseq

Jupyter Notebook 56 4 Updated May 30, 2022

Causal Mixture Model for GWAS summary statistics

C 75 20 Updated Dec 12, 2023

R-package for structural equation modeling based on GWAS summary data

R 232 58 Updated Jun 9, 2025

⛅ The right way to check the weather

Python 26,180 1,143 Updated Mar 4, 2025

Hypothesis Prioritisation in multi-trait Colocalization

R 53 12 Updated Apr 8, 2024

A collection of various utilities for GWAS summary statistics

Python 27 14 Updated May 14, 2024

Here we develop the software for the method LDpredfunct described in https://www.biorxiv.org/content/early/2018/07/24/375337

Python 17 8 Updated Aug 30, 2024

A deep learning-based tool to identify splice variants

Python 443 166 Updated Mar 19, 2024

The hap-ibd program detects identity-by-descent segments in phased genotype data.

Java 47 8 Updated Jun 11, 2024

FastSMC is a method to quickly and accurately estimate pairwise identical-by-descent (IBD) regions in the genome. FastSMC estimates the age of IBD segments and scales to large biobank datasets. htt…

Jupyter Notebook 14 1 Updated Sep 2, 2021

A step by step guide on how to use eMAGMA, an approach to conducting eQTL informed gene-based tests.

66 32 Updated Feb 4, 2021

Extracting meaningful health information from large accelerometer datasets

Python 210 68 Updated May 29, 2025

TOPMed analysis pipeline

R 52 32 Updated Oct 10, 2023

Colocalization analysis of genetic association signals

C++ 53 12 Updated May 12, 2025

R script that performs gene-set or gene property analysis using TWAS results.

R 31 6 Updated Sep 11, 2024
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