amber v4.1.1
·
871 commits
to master
since this release
Functional:
- modified contamination check conditions to consider low-VAF peak and any number of sites with 3+ reads
- default min map quality now 50 from 1
- disable min/max depth checks in target-regions mode
- min tumor default (config: tumor_min_depth) defaults to 25 for tumor/normal, 8 for tumor-only
- restrict sites to target regions in panel mode
Bugs:
- fixed restriction to panel regions in targeted mode
- ensure default min tumor depth (8) is applied in tumor/reference mode
Technical:
- handle multiple reference BAM samples in config
- handle empty sites file in PCF calls
Config:
- target_regions_bed - provide this file in targeted panel mode