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What is it for

imputeqc is an R package and accompanied scripts to estimate the quality of imputation of genotypes that was made with fastPHASE tool. It allows to choose the appropriate number of haplotype clusters (K) for the search of selection fingerprints with hapFLK test.

Ho to install from GitHub

  1. Make sure you have devtools package installed. Run from R
install.packages("devtools")
  1. Install imputeqc
devtools::install_github("inzilico/imputeqc", build_vignettes = TRUE)

How to use

Read a vignette How to Select the Number of Clusters for fastPHASE:

  • download *.pdf.
  • On a local machine, the vignette can be accessed as follow:
browseVignettes("imputeqc")
  • On remote machine, the vignette can be opened in the "Help" tab of RStudio:
vignette("k_selection")

Contacts

Gennady Khvorykh, a bioinformatician, inzilico.com

Interested in contributing to the project? Suggestions, questions, and comments are open! Feel free to drop me the message.

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An R package to estimate the quality of imputation of genotypes.

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