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Course tutorial for ActivityFlow fMRI analysis method(Cole et al., 2016)

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2021 Fall SKKU GBME "fMRI biomarker development 2" Week 2 - Activity Flow mapping

Reference papers

  • Cole, M. W., Ito, T., Bassett, D. S., & Schultz, D. H. (2016). Activity flow over resting-state networks shapes cognitive task activations. Nature Neuroscience, advance online publication. https://doi.org/10.1038/nn.4406
  • Ito, T., Hearne, L., Mill, R., Cocuzza, C., & Cole, M. W. (2020). Discovering the Computational Relevance of Brain Network Organization. Trends in Cognitive Sciences, 24(1), 25–38.
  • Sanchez-Romero, R., & Cole, M. W. (2020). Combining multiple functional connectivity methods to improve causal inferences. Journal of Cognitive Neuroscience, 1-15.

Software dependencies

You may need to install additional packages to proceed the tutorial.

  • Jupyter: pip install jupyter for development environment
  • Numpy: pip install numpy for numerical calculation
  • Matplotlib: pip install matplotlib for data visualization
  • scipy: pip install scipy for statistics
  • h5py: pip install h5py for HDF data read/write

You can download and install ActflowToolbox by run below command and it's recommended for end-users. but in this course tutorial, I won't use ActflowToolbox but I will proceed the tutorial by using basic scientific computing packages only.

  • ActflowToolbox: git clone --recurse-submodules https://github.com/ColeLab/ActflowToolbox.git

File structures

Some files are from ActflowToolbox by ColeLab (https://github.com/ColeLab/ActflowToolbox)

  • Tutorial.ipynb : Notebook file for ActivityFlow tutorial
  • HCP_example_data/ : HCP cognitive-task, resting-state fMRI data used in the tutorial
  • HCPMMP1_on_MNI152_ICBM2009a_nlin.nii.gz : Cortical atlas by Glasser et al., 2016
  • img/ : supplementary figures
  • cortex_parcel_network_assignments.txt : Assigned labels of large-scale functional network for each ROIs

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