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Analysis scripts and notebooks for Numbat paper

R 9 Updated Aug 12, 2022

The best free and open-source automated time tracker. Cross-platform, extensible, privacy-focused.

Python 14,421 654 Updated Feb 11, 2025

Fork from https://bitbucket.org/mcgranahanlab/lohhla/src, modified for MSKCC needs

R 31 10 Updated Jul 27, 2023
Python 18 7 Updated Mar 20, 2022

A tool for detecting somatic variants in single cell data

Python 205 30 Updated Sep 15, 2024

Neural Networks: Zero to Hero

Jupyter Notebook 13,896 1,931 Updated Aug 18, 2024

Draw phylogenetic trees of tumor evolution

Python 78 23 Updated Jul 21, 2023

Github for files currently published in the IPD-IMGT/HLA FTP Directory hosted at the European Bioinformatics Institute

Parrot 227 61 Updated Apr 29, 2025

Code accompanying The Evolutionary history of 2,658 cancers

46 7 Updated Apr 16, 2021

Efficient genotyping bi-allelic SNPs on single cells

C 143 12 Updated Jun 18, 2024

Haplotype-aware CNV analysis from single-cell RNA-seq

R 181 24 Updated May 19, 2025

MiXCR is an ultimate software platform for analysis of Next-Generation Sequencing (NGS) data for immune profiling.

Kotlin 356 80 Updated May 8, 2025
Python 157 69 Updated May 29, 2025

nextNEOpi: a comprehensive pipeline for computational neoantigen prediction

Nextflow 73 25 Updated May 19, 2025

Principal analysis code used in for analysis of single cell RNAseq of primary untreated colon cancer. As described in: "Spatially organized multicellular immune hubs in human colorectal cancer"

Jupyter Notebook 39 4 Updated Sep 5, 2021

Strelka2 germline and somatic small variant caller

C++ 369 104 Updated Dec 29, 2021

Tool to convert variants to mutated peptide sequences

R 1 Updated Oct 21, 2024

Inferring CNV from Single-Cell RNA-Seq

R 615 173 Updated Feb 1, 2025

Data processing and analysis related code associated with the study "A single-cell and spatially resolved atlas of human breast cancers".

R 113 51 Updated Sep 24, 2024

A library for creating complex UpSet plots with ggplot2 geoms

Jupyter Notebook 512 30 Updated Mar 9, 2024

R package for detecting doublets in single-cell RNA sequencing data

R 468 119 Updated Mar 21, 2025

Code relating to http://dx.doi.org/10.2139/ssrn.4132721

Jupyter Notebook 10 7 Updated Nov 24, 2022

TCR and BCR assembly from RNA-seq data

C 310 54 Updated Apr 30, 2025

MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data

HTML 147 17 Updated Jan 14, 2025

NicheNet: predict active ligand-target links between interacting cells

R 541 125 Updated May 27, 2025

A thorough tutorial on HLA imputation and association, accompanying our manuscript "Tutorial: A statistical genetics guide to identifying HLA alleles driving complex disease"

Jupyter Notebook 67 14 Updated Oct 10, 2024
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