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FEP-SPell-ABFE: An Open Source Alchemical Absolute Binding Free Energy Calculation Workflow for Drug Discovery

Python 63 12 Updated Jan 8, 2025

This is the offical codebase to reproduce and use EVOLVEpro, a model for in silico directed evolution of protein activities using few-shot active learning.

Python 256 58 Updated Mar 27, 2025

Proteina is a new large-scale flow-based protein backbone generator that utilizes hierarchical fold class labels for conditioning and relies on a tailored scalable transformer architecture.

Python 169 21 Updated May 27, 2025

Code for running RFdiffusion

Python 2,210 449 Updated Apr 11, 2025

Ready-to-go Jupyter notebook for plotting AlphaFold-generated MSAs, per-residue pLDDT, and PAE.

Jupyter Notebook 7 1 Updated Dec 20, 2024

In silico directed evolution of peptide binders with AlphaFold

Jupyter Notebook 182 39 Updated Jun 1, 2025

Attention Is All You Need | a PyTorch Tutorial to Transformers

Python 313 48 Updated Feb 22, 2024

In-depth tutorials for implementing deep learning models on your own with PyTorch.

1,541 226 Updated Dec 9, 2023

Colab Notebooks covering deep learning tools for biomolecular structure prediction and design

Jupyter Notebook 390 58 Updated Apr 3, 2025

python notebooks accompanying the book Make Your Own GAN

Jupyter Notebook 379 213 Updated Jun 23, 2021

A set of examples around pytorch in Vision, Text, Reinforcement Learning, etc.

Python 23,106 9,672 Updated May 18, 2025

AI-powered ab initio biomolecular dynamics simulation

Python 507 66 Updated Feb 18, 2025

Listing of papers about machine learning for proteins.

1,621 215 Updated May 31, 2024

User friendly and accurate binder design pipeline

Python 539 120 Updated Jun 2, 2025

Foldseek enables fast and sensitive comparisons of large structure sets.

C 983 125 Updated Jun 1, 2025

Democratizing Deep-Learning for Drug Discovery, Quantum Chemistry, Materials Science and Biology

Python 6,013 1,868 Updated May 21, 2025

整理一些书籍 ,包含 C&C++ 、git 、Java、Keras 、Linux 、NLP 、Python 、Scala 、TensorFlow 、大数据 、推荐系统、数据库、数据挖掘 、机器学习 、深度学习 、算法等。

966 291 Updated Sep 1, 2019

奈云VPN官网地址

29 2 Updated May 6, 2025

Jupyter Notebooks for learning the PyRosetta platform for biomolecular structure prediction and design

Jupyter Notebook 571 160 Updated Aug 12, 2024

Demos of many Rosetta applications

Roff 17 4 Updated May 28, 2025

Diffusion model based protein-ligand flexible docking method

Python 105 15 Updated Oct 30, 2024

GNN trained to predict changes in thermodynamic stability for protein point mutants

Python 171 33 Updated Feb 14, 2025

好的CADD教程,资源总结

24 8 Updated Apr 8, 2024

A Highly Opinionated List of Open Source Cheminformatics Resources

189 28 Updated Nov 19, 2020

TeachOpenCADD: a teaching platform for computer-aided drug design (CADD) using open source packages and data

Jupyter Notebook 866 213 Updated Mar 25, 2025

Linux Driver for RTL8821CU, RTL8811CU USB Wi-Fi NIC

C 49 16 Updated Sep 24, 2021

Public RFDiffusionAA repo

Python 395 75 Updated Jul 9, 2024

List of papers about Proteins Design using Deep Learning

1,681 196 Updated May 30, 2025
Jupyter Notebook 165 39 Updated Oct 27, 2021
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